• Backbone structures are obtained using ProteinViewer, where N-terminal is colored red and C-terminal blue.
• Click the images to view larger image.
• Click PDB IDs to view the corresponding PDB file
• See the bottom for brief explanation of the DSSP codes and the 5-tile codes. 
• The "site" row indicates active site residues:
          "*" denotes active sites registered in SwissProt/UniProt.
          "+" denotes active sites registered in PROSITE/UniProt.
           Residues registered in both of them are denoted by "*."
• In the images of superimposition, the C-terminal of the first sequence is connected with the N-terminal of the second sequecne
  (because of the DaliLite output format).
  

(1) Cluster 11

				Z-Score: 20.0 AR: 177 RMSD: 12.1A SI: 100%
1dcl A (len 216)	1dcl B (len 216)		DaliLite result

site  1dcA PSALTQPPSASGSLGQSVTISCTGT  SSN VGGYNYVSWYQQHAGKAPKVIIYEVNKRPSGVPDRFSGSKSGNTASLTVSGLQAED EADYYC code --000003000000RG000000000  0RR 0R001R00000000RG0000000RO00001RG0QBG000000RG000000R00QAB G00000 LCS    00000 000000RG000000000  0   0R   R00000000RG0000 00RO0000 R 0QBG000000RG000000R00QAB G00000 code --00000R000000RG000000000QB0QAG0R   R00000000RG0000R00RO00000R00QBG000000RG000000R00QABRG00000 1dcB PSALTQPPSASGSLGQSVTISCTGTSSNVGGYN   YVSWYQQHAGKAPKVIIYEVNKRPSGVPDRFSGSKSGNTASLTVSGLQAEDEADYYCS site  site  1dcA SSY EGSDNFVFGTGTKVTVLGQPKANPTVTLFPPSSEELQANKATLVCLISDFYPGAVTVAWKADGSPVKAGVETTKPSKQSNNKYAASS code 000 RO0RG0000R00000R0R00000000000000QAAAABRG00000000R00O0G0000000RRG0000O000000000QBRG00000 LCS  00  R  R 0000 00000 0R00000000000000QAAAAB G00000000R00O0 0000000RRG00   000000000Q RG00000 code 0031R  R0000000000000R00000000000000QAAAAB0G00000000R00O000000000RRG00RGR000000000QGRG00000 1dcB SYEGS  DNFVFGTGTKVTVLGQPKANPTVTLFPPSSEELQANKATLVCLISDFYPGAVTVAWKADGSPVKAGVETTKPSKQSNNKYAASS site  site               +++++++ 1dcA YLSLTPEQWKSHRSYSCQVTHEGSTVEKTVAPTECS code 00000QAAAABGR00000000ORG0000000000-- LCS  00000QAAA BGR00000000 RG0000000  0 code 00000QAAAHBGR00000000RRG0000000RG0-- 1dcB YLSLTPEQWKSHRSYSCQVTHEGSTVEKTVAPTECS site               +++++++ *RATIO :  lcs/trimmed_seq_a = 0.882 (=  187/  212), lcs/trimmed_seq_b = 0.882 (=  187/  212)

Structural alignment by ComSubstruct + manual inspection

DSSP LLLEELLLEEEELLLLLEEEEEEELLLLLlLLLLEEEEEELLLLLLEEEELLLLLLLLLLLLLEEEEELLLEEEEEELLLLHHHLEEEEE 1dcA PSALTQPPSASGSLGQSVTISCTGTSSNVgGYNYVSWYQQHAGKAPKVIIYEVNKRPSGVPDRFSGSKSGNTASLTVSGLQAEDEADYYC      ||||||||||||||||||||||||||||| |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1dcB PSALTQPPSASGSLGQSVTISCTGTSSNVgGYNYVSWYQQHAGKAPKVIIYEVNKRPSGVPDRFSGSKSGNTASLTVSGLQAEDEADYYC DSSP LLEELLLLLLLEELLLEEEEEEELLLLLLlLLLLEEEEEELLLLLEEEEELLLLLLLLLLLLLEEEEELLLEEEEEEELLLLLLLEEEEE DSSP EELLLLLLLEELLLEEEEELLLLLLllEEEEELLLHHHHLLLLEEEEEEEEEELlllleeeeeelleelllleeellLEELLLLLEEEEE 1dcA SSYEGSDNFVFGTGTKVTVLGQPKAnpTVTLFPPSSEELQANKATLVCLISDFYpgavtvawkadgspvkagvettkPSKQSNNKYAASS      |||||||||||||||||||||||||  |||||||||||||||||||||||||||                       ||||||||||||| 1dcB SSYEGSDNFVFGTGTKVTVLGQPKAnpTVTLFPPSSEELQANKATLVCLISDFYpgavtvawkadgspvkagvettkPSKQSNNKYAASS DSSP EEELLLLLEEEELLLEELEELLLLLllEEEEELLLHHHHLLLLEEEEEEEEEELllleeeeeeelleeellleeellLEELLLLLEEEEE DSSP EEEELHHHHHHLLLEeeeeelllleeeEEELLLLLl 1dcA YLSLTPEQWKSHRSYscqvthegstveKTVAPTECs      |||||||||||||||            |||||||| 1dcB YLSLTPEQWKSHRSYscqvthegstveKTVAPTECs DSSP EEEELHHHHHHLLLEeeeeeelleeeeEEELLLLLl *Z-score 20.0  AR 177  RMSD 12.1A  SI 100%

Structural alignment by DaliLite

(2) Cluster 12

				Z-Score: 43.0 AR: 427 RMSD: 10.8A SI: 99%
1ddt (len 523)	1mdt A (len 523)		DaliLite result

site                    *                                           * 1ddt GADDVVDSSKSFVMENFSSYHGTKPGYVDSIQKGIQKPKSGTQGNYDDDWKGFYSTDNKYDAAGYSVDNENPLSGKAGGVVKVTYPGLTK code --AB00OQABG0000R000000000AHQ1AAAB00000RG0RRR0RGQAG000000RGQAAAAABG00QB3QB00000000000000000 LCS    AB00 QABG0000R000000000 HQ AAAB00000R 0RRR0RGQAG000000RGQAAAAA  00QB QB00000000000000000 code --AB0G0QABG0000R000000000QHQHAAAB00000R00RRR0RGQAG000000RGQAAAAAAJ00QB0QB00000000000000000 1mdt GADDVVDSSKSFVMENFSSYHGTKPGYVDSIQKGIQKPKSGTQGNYDDDWKGFYSTDNKYDAAGYSVDNENPLSGKAGGVVKVTYPGLTK site                    *                                           * site                                                         *    * 1ddt VLALKVDNAETIKKELGLSLTEPLMEQVGTEEFIKRFGDGASRVVLSLPFAEGSSSVEYINNWEQAKALSVELEINFETRGKRGQDAMYE code 0000R0RGQAAAAAABR00QGG0QAAAABGQAAAAB1RRR0R0000000R00RGRG000000QAAAABG0000R0RQAABR000RQAAAA LCS  0000R0R QAAAAAABR00Q G0 AAAABGQAAAA 1 RR0R0000000R00RGRG000000QAAAABG0000R0 QAABR000RQAAAA code 0000R0R0QAAAAAABR00QBG0PAAAABGQAAAAG1ORR0R0000000R00RGRG000000QAAAABG0000R00QAABR000RQAAAA 1mdt VLALKVDNAETIKKELGLSLTEPLMEQVGTEEFIKRFGDGASRVVLSLPFAEGSSSVEYINNWEQAKALSVELEINFETRGKRGQDAMYE site                                                         *    * site  1ddt YMAQACASCINLDWDVIRDKTKTKIESLKEHGPIKNKMSESPNKTVSEEKAKQYLEEFHQTALEHPELSELKTV  TGTNPVFAGANYAAWA code AAAAABPJ0000RQAAAAAAAAAAAAAAABGPAAAAAAABGRRG000QAAAAAAAAAAAAAAABGQABHAAAAA  BG0GQAB0QAAAAAAA LCS  AAAAABPJ0000RQAAAAAAAAAAAAAAAB  AAAAAAABGRRG000QAAAAAAAAAAAAAAAB QAB AAAAA  B 0 QAB0QAAAAAAA code AAAAABPJ0000RQAAAAAAAAAAAAAAAB0QAAAAAAABGRRG000QAAAAAAAAAAAAAAAB0QABQAAAAAAAB 0 QAB0QAAAAAAA 1mdt YMAQACASCINLDWDVIRDKTKTKIESLKEHGPIKNKMSESPNKTVSEEKAKQYLEEFHQTALEHPELSELKTVTGT N PVFAGANYAAWA site  site  1ddt VNVAQVIDSETADNLEKTTAALSILPGIGSVMGIADGAVHHNTE EIVAQSIALSSLMVAQAIPLVGELVDIGF  AAYNFVESIINLFQVVH code AAAAABG0QAAABGQAAAAAAAABG00QAAABR00RRG0QB0GQ AAAAAAAAAAAAAAAAAAAB0000RQBHQ  AB0QAAAAAAAAAAAAA LCS  AAAAABG0QAAABGQAAAAAAAABG0 QAAABR00RRG QB0GQ AAAAAAAAAAAAAAAAAA  000 R   Q  AB0QAAAAAAAAAAAAA code AAAAABG0QAAABGQAAAAAAAABG0RQAAABR00RRGRQB0GQHAAAAAAAAAAAAAAAAAAJ 000RR0  QAAAB0QAAAAAAAAAAAAA 1mdt VNVAQVIDSETADNLEKTTAALSILPGIGSVMGIADGAVHHNTEEIVAQSIALSSLMVAQAIPL VGELVD  IGFAAYNFVESIINLFQVVH site  site  1ddt NSYNRPAYSPGHKTQPFLH DGYAVSWNTVEDSI I  RTGFQGESGHDIKITAENTPLPIAGVLLPTIPGK LDVNKSKTHISVNGRKIRMRCR code AAABG00000RG0R00000 RRG0000R0QAABG 0  013G0000000000000000000R00000000QB 000RQABG0000RR00000000 LCS  AAABG000  RG0R00000 RRG0000R0QAABG 0  0   0000000000000000000R000000  QB 000RQABG0000RR00000000 code AAABG000R RG0R000000RRG0000R0QAABGO0QB0   0000000000000000000R000000R QB0000RQABG0000RR00000000 1mdt NSYNRPAYS PGHKTQPFLHDGYAVSWNTVEDSIIRTGF   QGESGHDIKITAENTPLPIAGVLLPTI PGKLDVNKSKTHISVNGRKIRMRCR site  site  1ddt AIDGDVTFCRPKSPVYVGNGVHANLHVAFHRSSSEKIHSNEISSDSIGVLGYQKTVDHTKVNSKLSLFFEIKS code 001RR000000R0000000RG0000000000RGRG000QABGRGRG00000000R0RRG000000000000-- LCS  00 RR000000R000000 RG0000000000RGR 000QABGR RG00000000 0RRG00000000000 code 000RR000000R000000RRG0000000000RGRO000QABGR0RG0000000000RRG00000000000O-- 1mdt AIDGDVTFCRPKSPVYVGNGVHANLHVAFHRSSSEKIHSNEISSDSIGVLGYQKTVDHTKVNSKLSLFFEIKS site  *RATIO :  lcs/trimmed_seq_a = 0.923 (=  479/  519), lcs/trimmed_seq_b = 0.923 (=  479/  519)

Structural alignment by ComSubstruct + manual inspection

DSSP LHHHLLLHHHLEEEELLEEEEEELLLLLLHHHHLLLLLLLLLLLLLLHHHLLEEEELLHHHHHHHLLLLLLLLLLLLLEEEEEELLLEEE 1ddt GADDVVDSSKSFVMENFSSYHGTKPGYVDSIQKGIQKPKSGTQGNYDDDWKGFYSTDNKYDAAGYSVDNENPLSGKAGGVVKVTYPGLTK      |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1mdt GADDVVDSSKSFVMENFSSYHGTKPGYVDSIQKGIQKPKSGTQGNYDDDWKGFYSTDNKYDAAGYSVDNENPLSGKAGGVVKVTYPGLTK DSSP LHHHLEEEEEEEEEELLEEEEEELLLLLLHHHHLLLLLLLLLLLLLLHHHLLEEEELLHHHHHLLLLLLLLLLLLLLLEEEEEELLLEEE DSSP EEELLLLLHHHHHHHLLLLLLLLHHHHHLLHHHHHHHLLLLLEEEEEEELLLLLLLEEEEELLLHHHHLEEEEEEELHHHLLLLLHHHHH 1ddt VLALKVDNAETIKKELGLSLTEPLMEQVGTEEFIKRFGDGASRVVLSLPFAEGSSSVEYINNWEQAKALSVELEINFETRGKRGQDAMYE      |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1mdt VLALKVDNAETIKKELGLSLTEPLMEQVGTEEFIKRFGDGASRVVLSLPFAEGSSSVEYINNWEQAKALSVELEINFETRGKRGQDAMYE DSSP EEEELLLLHHHHHHHLLLLLLLLHHHHLLLHHHHHHHLLLLLEEEEEEELLLLLLLEEEEELLLHHHHLEEEEEEELHHHLLLLLHHHHH DSSP HHHHHHLLLLLLLHHHHHHHHHHHHHHHHHLHHHHHHHHHLLLLLLLHHHHHHHHHHHHHHHLLLHHHHHHHHHLLLLHHHLHHHHHHHH 1ddt YMAQACASCINLDWDVIRDKTKTKIESLKEHGPIKNKMSESPNKTVSEEKAKQYLEEFHQTALEHPELSELKTVTGTNPVFAGANYAAWA      |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1mdt YMAQACASCINLDWDVIRDKTKTKIESLKEHGPIKNKMSESPNKTVSEEKAKQYLEEFHQTALEHPELSELKTVTGTNPVFAGANYAAWA DSSP HHHHLLLLLLLLLHHHHHHHHHHHHHHHHLLHHHHHHHHLLLLLLLLHHHHHHHHHHHHHHHLLLHHHHHHHHHHLLLHHHLHHHHHHHH DSSP HHHHLLLLHHHHLLHHHHHHHHLLLLLHHHHHLEELLEELLLLHHHHHHHHHHHHHHHHHHHHHHLLLLLHHHHHLHHHHHHHHHHHHHH 1ddt VNVAQVIDSETADNLEKTTAALSILPGIGSVMGIADGAVHHNTEEIVAQSIALSSLMVAQAIPLVGELVDIGFAAYNFVESIINLFQVVH      |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1mdt VNVAQVIDSETADNLEKTTAALSILPGIGSVMGIADGAVHHNTEEIVAQSIALSSLMVAQAIPLVGELVDIGFAAYNFVESIINLFQVVH DSSP HHHHHHLLHHHHLLHHHHHHHHLLLLLHHHHHLEELLEELLLLHHHHHHHHHHHHHHHHHHHHHHLLLLLHHHHHLHHHHHHHHHHHHHH DSSP HHHHLLLLlllllLLLEEELLEEEEELLLHHHEEELllleeeeeeeeeeelllleeeleeEEELLLllleellllleeeelleeeeeeee 1ddt NSYNRPAYspghkTQPFLHDGYAVSWNTVEDSIIRTgfqgesghdikitaentplpiagvLLPTIPgkldvnkskthisvngrkirmrcr      ||||||||     |||||||||||||||||||||||                        |||||| 1mdt NSYNRPAYspghkTQPFLHDGYAVSWNTVEDSIIRTgfqgesghdikitaentplpiagvLLPTIPgkldvnkskthisvngrkirmrcr DSSP HHHLLLLLlllllLLLEEELLEEEEELLLHHHEEELlllleeeeeeeeeelllleeeleeEEELLLlleeellllleeeelleeeleeee DSSP ELLLLEE.eeeellleeellllleeeeeeeeellllLLLLlLLLLLEEEEeeeeelhhhlleeeEEEEELEEEL 1ddt AIDGDVT.fcrpkspvyvgngvhanlhvafhrssseKIHSnEISSDSIGVlgyqktvdhtkvnsKLSLFFEIKS      |||||||                                  |||||||||              |||||||||| 1mdt AIDGDVTfcrpkspvyvgngvhanlhvafhrsssekIHSN.EISSDSIGVlgyqktvdhtkvnsKLSLFFEIKS DSSP EELLLEEeeeellleeellllleeeeeeeeelllllLLLL.LLLLLEEEEeeeeeeelleeeeeEEEEELEEEL *Z-score 43.0  AR 427  RMSD 10.8A  SI 99%

Structural alignment by DaliLite

(3) Cluster 13

				Z-Score: 27.2 AR: 190 RMSD: 2.0A SI: 98%
1esg B (len 212)	2bam A (len 207)		DaliLite result

site                                                                                 * 1esg MEVEKEFITDEAKELLSKDKLIQQAYNEVKTSICSPIWPATSKTFTINNTEKNCNGVVPIKELCYTLLEDT Y NWYR  EKPLDILKLEKKKG code --0000000QAAAAAAA0GQAAAAAAAAAAAAAABG00OQBGRG0000RR00RRG01QAAAAAAAAAA8B0 0 R000  00QAAAAB1RR030 LCS    0000000QAAAAAA 0GQAAAAAAAAAAAAAABG00OQBGRG0000 R00RRG01QAA  AAAAA  B0 0 R000  00QA     RR  0 code --0000000QAAAAAAB0GQAAAAAAAAAAAAAABG00OQBGRG00000R00RRG01QAABHAAAAA  B0R0BR000R000QAG000 RRG 0 2bam MEVEKEFITDEAKELLSKDKLIQQAYNEVKTSICSPIWPATSKTFTINNTEKNCNGVVPIKELCYTL  LEDTYNWYREKPLDILKLE KKK G site                                                                               * site    *                  *** 1esg GPIDVYKEFIENSE  LKRVGMEFETGNISSAHRSMNKLLLGLKHGEIDLAIILMPIKQLAYYLTDRVTNFEELEPY FELTEGQPFIFIGFN code 000R000000R1R0  000000000RG0QAAAAAAAAAAAAAAABRR0R00000000QAAAABG00R000QAABAAA QAAB1RG00000000 LCS  000R000000   0  000000000RG0QAAAAAAAAAAAAAAABRR0R00000000QAAAABG00R000QAA AAA QAAB RG00000000 code 000R0000000  0RG000000000RG0QAAAAAAAAAAAAAAABRR0R00000000QAAAABG00R000QAA AAABQAAB0RG00000000 2bam GPIDVYKEFIE  NSELKRVGMEFETGNISSAHRSMNKLLLGLKHGEIDLAIILMPIKQLAYYLTDRVTNFEE LEPYFELTEGQPFIFIGFN site    *                  *** site  1esg AEAYNSNVPL IPK    GSDGMSKRSIKKWKDKVEN code 0R000QBG00 000    0QBR00QAAAAAAAAAA-- LCS  0R000QBG00 000    0QB 00 code 0R000QBG00R000R00R0QBG00R-- 2bam AEAYNSNVPLIPKGSDGMSKRSIKKWK site  *RATIO :  lcs/trimmed_seq_a = 0.856 (=  178/  208), lcs/trimmed_seq_b = 0.877 (=  178/  203)

Structural alignment by ComSubstruct + manual inspection

DSSP LEEEEEEELHHHHHHHHHLHHHHHHHHHHHHHHHLLLLLLLLLLLEEELLLLLLLLLHHHHHHHHHHHHHHHLLEEL.lhhhhHHHLLLlL 1esg MEVEKEFITDEAKELLSKDKLIQQAYNEVKTSICSPIWPATSKTFTINNTEKNCNGVVPIKELCYTLLEDTYNWYRE.kpldiLKLEKKkG      |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||          || | 2bam MEVEKEFITDEAKELLSKDKLIQQAYNEVKTSICSPIWPATSKTFTINNTEKNCNGVVPIKELCYTLLEDTYNWYREkpldilKLEKKK.G DSSP LEEEEEEELHHHHHHHHHLHHHHHHHHHHHHHHLLLLLLLLLLLLEELLLLLLLLLLHHHHHHHHHHHHLLLLLEEEellhhhHLLLLL.L DSSP LLLLEEEEEELLLLEEEEEEEELLLLHHHHHHHHHHHHHHHHLLLLLEEEEEEELHHHHLLLLLLLLLHHHHHHHHHHHLLLLEEEEEEE 1esg GPIDVYKEFIENSELKRVGMEFETGNISSAHRSMNKLLLGLKHGEIDLAIILMPIKQLAYYLTDRVTNFEELEPYFELTEGQPFIFIGFN      |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 2bam GPIDVYKEFIENSELKRVGMEFETGNISSAHRSMNKLLLGLKHGEIDLAIILMPIKQLAYYLTDRVTNFEELEPYFELTEGQPFIFIGFN DSSP LLEEEEEEEEELLEEEEEEEEELLLLHHHHHHHHHHHHHHHHLLLLLEEEEEEELHHHHLLLLLLLLLHHHHHHHHHHHLLLLEEEEEEE DSSP LLEEELLLLLLLLLLLlllllhhhhhhhhhhl 1esg AEAYNSNVPLIPKGSDgmskrsikkwkdkven      |||||||||||||||| 2bam AEAYNSNVPLIPKGSD.....gmskrsikkwk DSSP LLEELLLLLLLLLLLL.....lllllllllll *Z-score 27.2  AR 190  RMSD 2.0A  SI 98%

Structural alignment by DaliLite

(3-2)

				Z-Score: 33.0 AR: 196 RMSD: 1.1A SI: 100%
2bam A (len 207)	2bam B (len 210)		DaliLite result

site                                                                               * 2baA MEVEKEFITDEAKELL SKDKLIQQAYNEVKTSICSPIWPATSKTFTINN TEKNCNGVVPIKELCYTLLEDTYNWYREKPLDILK LEKKKG code --0000000QAAAAAA B0GQAAAAAAAAAAAAAABG00OQBGRG00000 R00RRG01QAABHAAAAAB0R0BR000R000QAG0 00RRG0 LCS    0000000QAAAAAA B GQAAAAAAAAAAAAAABG0  QBGR 00000 R00RRG01 AAB AAAAA 0 0BR000 000Q  0 00RRG0 code --0000000QAAAAAAGB GQAAAAAAAAAAAAAABG01RQBGR 00000OR00RRG01HAABQAAAAAA000BR0000000QB 0B00RRG0 2baB MEVEKEFITDEAKELLSK DKLIQQAYNEVKTSICSPIWPATSK TFTINNTEKNCNGVVPIKELCYTLLEDTYNWYREKPLDI LKLEKKKG site                                                                               * site    *                *** 2baA GPIDVYKEFIENSELKRVGMEFETGNISSAHRSMNKLLLGLKHGEIDLAIILMPIKQLAYYLTDRVTNFEE LEPYFELTEGQPFIFIGFN code 000R00000000RG000000000RG0QAAAAAAAAAAAAAAABRR0R00000000QAAAABG00R000QAA AAABQAAB0RG00000000 LCS  000R00000000RG0000000 0RG0QAAAAAAAAAAAAAAABRR0R00000000QAAAABG00R000QAA AAA QAAB0RG00000000 code 000R00000000RG0000000R0RG0QAAAAAAAAAAAAAAABRR0R00000000QAAAABG00R000QAABAAA QAAB0RG00000000 2baB GPIDVYKEFIENSELKRVGMEFETGNISSAHRSMNKLLLGLKHGEIDLAIILMPIKQLAYYLTDRVTNFEELEPY FELTEGQPFIFIGFN site    *                *** site  2baA AEAYNSNVPLIPKG     SDGMSKRSIKKWK code 0R000QBG00R000     R00R0QBG00R-- LCS  0R000QBG00R000     R00 0   00 code 0R000QBG00R000QABG0R00 0   00QAB-- 2baB AEAYNSNVPLIPKGSDGMSKRS I   KKWKDKV site  *RATIO :  lcs/trimmed_seq_a = 0.911 (=  185/  203), lcs/trimmed_seq_b = 0.898 (=  185/  206)

Structural alignment by ComSubstruct + manual inspection

DSSP LEEEEEEELHHHHHHHHHLHHHHHHHHHHHHHHLLLLLLLLLLLLEELLLLLLLLLLHHHHHHHHHHHHLLLLLEEEELLHHHHLLLLLL 2baA MEVEKEFITDEAKELLSKDKLIQQAYNEVKTSICSPIWPATSKTFTINNTEKNCNGVVPIKELCYTLLEDTYNWYREKPLDILKLEKKKG      |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 2baB MEVEKEFITDEAKELLSKDKLIQQAYNEVKTSICSPIWPATSKTFTINNTEKNCNGVVPIKELCYTLLEDTYNWYREKPLDILKLEKKKG DSSP LEEEEEEELHHHHHHHHHLHHHHHHHHHHHHHHHLLLLLLLLLLLEEELLLLLLLLLHHHHHHHHHHHHHLLLLEEEELLHHHHLLLLLL DSSP LLEEEEEEEEELLEEEEEEEEELLLLHHHHHHHHHHHHHHHHLLLLLEEEEEEELHHHHLLLLLLLLLHHHHHHHHHHHLLLLEEEEEEE 2baA GPIDVYKEFIENSELKRVGMEFETGNISSAHRSMNKLLLGLKHGEIDLAIILMPIKQLAYYLTDRVTNFEELEPYFELTEGQPFIFIGFN      |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 2baB GPIDVYKEFIENSELKRVGMEFETGNISSAHRSMNKLLLGLKHGEIDLAIILMPIKQLAYYLTDRVTNFEELEPYFELTEGQPFIFIGFN DSSP LLEEEEEEEEELLEEEEEEEEELLLLHHHHHHHHHHHHHHHHLLLLLEEEEEEELHHHHLLLLLLLLLHHHHHHHHHHHLLLLEEEEEEE DSSP LLEELLLLLLLLLLLL...lllllllllll 2baA AEAYNSNVPLIPKGSD...gmskrsikkwk      |||||||||||||||| 2baB AEAYNSNVPLIPKGSDgmskrsikkwkdkv DSSP LLEEELLLLLLLLHHHhllllllllhhhll *Z-score 33.0  AR 196  RMSD 1.1A  SI 100%

Structural alignment by DaliLite

(4) Cluster 14

			No Sigificant Similarities	Z-Score: - AR: - RMSD: -A SI: -%
1ets L (len 36)	1ucy L (len 36)		DaliLite result

site                                                                                         1ets TFGAGEADCGLRPLFEKKQVQDQTEKELFESYIEGR code --0000001RG02B0QABR000QBQAAAAAAAAB-- LCS    00     RG0 B0QABR000  QAAAAA   B code --00QBQBGRG0QB0QABR000R1QAAAAA   BHRR-- 1ucy TFGAGEADCGLRPLFEKKQVQDQTEKELFE   SYIEGR site *RATIO :  lcs/trimmed_seq_a = 0.656 (=   21/   32), lcs/trimmed_seq_b = 0.656 (=   21/   32)

Structural alignment by ComSubstruct + manual inspection

DSSP  1ets       1ucy DSSP *Z-score -  AR -  RMSD -A  SI -%

Structural alignment by DaliLite

(5) Cluster 15

				Z-Score: 60.5 AR: 350 RMSD: 1.6A SI: 100%
1fdj A (len 363)	1fdj C (len 363)		DaliLite result

site                                                       * 1fdA AHRFPALTPEQKKELSDIAQRIVANGKGILAADESVGTMGNRLQRIKVENSEENRRQFREILFTVDNSINQSIGGVILFHETLYQKDSQG code --AG0R00QAAAAAAAAAAAAAB0RR0000RRR00QAAAAAAAAABR0000QAAAAAAAAAAAB00QAAAB00R00000QAAABG00QBR LCS    AG0R00QAAAAAAAAAAAAAB0RR0000 RR00QAAAAAAAAABR0000QAAAAAAAAAAAB00QAAAB00R00000QAAABG00QBR code --AG0R00QAAAAAAAAAAAAAB0RR00000RR00QAAAAAAAAABR0000QAAAAAAAAAAAB00QAAAB00R00000QAAABG00QBR 1fdC AHRFPALTPEQKKELSDIAQRIVANGKGILAADESVGTMGNRLQRIKVENSEENRRQFREILFTVDNSINQSIGGVILFHETLYQKDSQG site                                                       * site                                                          * 1fdA KLFRNILKEKGIVVGIKLDQGGAPLAGTNKE TTIQ GLDGLSERCAQYKKDGVDFGKWRAVLRIADQCPSSLAIQENANTLARYASICQQN code 00QAAAAAABR0000000GR000000RGRR0 0000 1RGRQAAAAAAAAAB000000000000000R0O0QAAAAAAAAAAAAAAAAAAAB LCS  00QAAAAAABR0000000GR000000RG  0 0000 1RGRQAAAAAAAAAB 00000000000000R0O0QAAAAAAAAAAAAAAAAAAAB code 00QAAAAAABR0000000GR000000RG  0R000011RGRQAAAAAAAAABR00000000000000R0O0QAAAAAAAAAAAAAAAAAAAB 1fdC KLFRNILKEKGIVVGIKLDQGGAPLAGT  NKETTIQGLDGLSERCAQYKKDGVDFGKWRAVLRIADQCPSSLAIQENANTLARYASICQQN site                                                        * site       *                                           * 1fdA GLVPIVEPEVIPD  GDHDLEHCQYVTEKVLAAVYKALNDHHVYLEGTLLKPNMVTAGHACTKKYTPEQVAMATVTALHRTVPAAVPGICFL code R000000R0R0R0  0R00QAAAAAAAAAAAAAAAAAAAABR00QABG0000000000QBGRG000QAAAAAAAAAAAAB000QBGR00000 LCS  R000000R0 0 0  0R00QAAAAAAAAAAAAAAAAAAAABR0 QABG0000000000QBGRG000QAAAAAAAAAA AB000QBGR00000 code R000000R0 0 0RG0R00QAAAAAAAAAAAAAAAAAAAABR0RQABG0000000000QBGRG000QAAAAAAAAAAHAB000QBGR00000 1fdC GLVPIVEPE V IPDGDHDLEHCQYVTEKVLAAVYKALNDHHVYLEGTLLKPNMVTAGHACTKKYTPEQVAMATVTALHRTVPAAVPGICFL site       *                                           * site  1fdA SGGMSEEDATLNLNAINLCPLPKPWKLSFSYGRALQASALAAWGGKAENKKATQEAFMKRAVVNCQAAKGQYVHTGSSGAAST Q SLFTA  S YTY code RRR00QAAAAAAAAAAABGRG00RG0000R00QAB1QAAAAAGRR0QABQAAAAAAAAAAAAAAAAAABRR000R000000QB R 000RG  G 0-- LCS  RRR00QAAAAAAAAAAABGRG00RG0000 00QA 1QAAAAA RR QABQAAAAAAAAAAAAAAAAAABR 000     00QB R 000RG  G 0 code RRR00QAAAAAAAAAAABGRG00RG0000000QAG1QAAAAABRRGQABQAAAAAAAAAAAAAAAAAABRG000     00QB1RG000RG0RG00-- 1fdC SGGMSEEDATLNLNAINLCPLPKPWKLSFSYGRALQASALAAWGGKAENKKATQEAFMKRAVVNCQAAKGQYVH     TGSSGAASTQSLFTASYTY site  *RATIO :  lcs/trimmed_seq_a = 0.950 (=  341/  359), lcs/trimmed_seq_b = 0.950 (=  341/  359)

Structural alignment by ComSubstruct + manual inspection

DSSP LLLLLLLLHHHHHHHHHHHHHHHHHHLEEEEELLLHHHHHHHHHHLLLLLLHHHHHHHHHHHHLLLHHHHHLEEEEEELHHHHLLLLLLL 1fdA AHRFPALTPEQKKELSDIAQRIVANGKGILAADESVGTMGNRLQRIKVENSEENRRQFREILFTVDNSINQSIGGVILFHETLYQKDSQG      |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1fdC AHRFPALTPEQKKELSDIAQRIVANGKGILAADESVGTMGNRLQRIKVENSEENRRQFREILFTVDNSINQSIGGVILFHETLYQKDSQG DSSP LLLLLLLLHHHHHHHHHHHHHHHHHHLEEEEELLLHHHHHHHHHHLLLLLLHHHHHHHHHHHHLLLHHHHHLEEEEEELLLHHHLLLLLL DSSP LLHHHHHHHLLLEEEEELLLLEEELLLLLLLEEELLLLLHHHHHHHHHHLLLLEEEEEEEELLLLLLLLHHHHHHHHHHHHHHHHHHHHL 1fdA KLFRNILKEKGIVVGIKLDQGGAPLAGTNKETTIQGLDGLSERCAQYKKDGVDFGKWRAVLRIADQCPSSLAIQENANTLARYASICQQN      |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1fdC KLFRNILKEKGIVVGIKLDQGGAPLAGTNKETTIQGLDGLSERCAQYKKDGVDFGKWRAVLRIADQCPSSLAIQENANTLARYASICQQN DSSP LLHHHHHHHLLLEEEEELLLLEEELLLLLLLEEELLLLLHHHHHHHHHHLLLLEEEEEEEELLLLLLLLHHHHHHHHHHHHHHHHHHHHL DSSP LLEEEEEEEELLLLLLLHHHHHHHHHHHHHHHHHHHHHLLLLHHHLEELLLLLLLLLLLLLLLLHHHHHHHHHHHHHLLLLLLLLEEEEL 1fdA GLVPIVEPEVIPDGDHDLEHCQYVTEKVLAAVYKALNDHHVYLEGTLLKPNMVTAGHACTKKYTPEQVAMATVTALHRTVPAAVPGICFL      |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1fdC GLVPIVEPEVIPDGDHDLEHCQYVTEKVLAAVYKALNDHHVYLEGTLLKPNMVTAGHACTKKYTPEQVAMATVTALHRTVPAAVPGICFL DSSP LLEEEEEEEELLLLLLLHHHHHHHHHHHHHHHHHHHHHLLLLHHHLEELLLLLLLLLLLLLLLLHHHHHHHHHHHHHHHLLLLLLEEEEL DSSP LLLLLHHHHHHHHHHHHHLLLLLLLEEEEEELHHHHHHHHHHHLLLHHHHHHHHHHHHHHHHHHHHHLLLLLLLLLLLLLlllllllllllll 1fdA SGGMSEEDATLNLNAINLCPLPKPWKLSFSYGRALQASALAAWGGKAENKKATQEAFMKRAVVNCQAAKGQYVHTGSSGAastqslftasyty      |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1fdC SGGMSEEDATLNLNAINLCPLPKPWKLSFSYGRALQASALAAWGGKAENKKATQEAFMKRAVVNCQAAKGQYVHTGSSGAastqslftasyty DSSP LLLLLHHHHHHHHHHHHHLLLLLLLEEEEEELHHHHHHHHHHHLLLHHHHHHHHHHHHHHHHHHHHHLLLLLLLLLLLLLlllllllllllll *Z-score 60.5  AR 350  RMSD 1.6A  SI 100%

Structural alignment by DaliLite

(5-2)

				Z-Score: 60.4 AR: 347 RMSD: 0.8A SI: 100%
1fdj A (len 363)	1fdj D (len 363)		DaliLite result

site                                                        * 1fdA AHRFPALTPEQKKELSDIAQRIVANGKGILAADESVGTMGNRLQRI KVENSEENRRQFREILFTVDNSINQSIGGVILFHETLYQKDSQG code --AG0R00QAAAAAAAAAAAAAB0RR0000RRR00QAAAAAAAAAB R0000QAAAAAAAAAAAB00QAAAB00R00000QAAABG00QBR LCS    AG0R00QAAAAAAAAAAAAAB0RR0000 RR00QAAAAAAAA B R0000QAAAAAAAAAAAB00QAAAB00R00000QAAABG00QBR code --AG0R00QAAAAAAAAAAAAAB0RR00000RR00QAAAAAAAA B0R0000QAAAAAAAAAAAB00QAAAB00R00000QAAABG00QBR 1fdD AHRFPALTPEQKKELSDIAQRIVANGKGILAADESVGTMGNRLQ RIKVENSEENRRQFREILFTVDNSINQSIGGVILFHETLYQKDSQG site                                                        * site                                                          * 1fdA KLFRNILKEKGIVVGIKLDQGGAPLAGTNKE TTIQG LDGLSERCAQYKKDGVDFGKWRAVLRIADQCPSSLAIQENANTLARYASICQQN code 00QAAAAAABR0000000GR000000RGRR0 0000 1RGRQAAAAAAAAAB000000000000000R0O0QAAAAAAAAAAAAAAAAAAAB LCS  00QAAAAAABR0000000GR000000RG  0 0000 1RGRQAAAAAAAAAB 00000000000000R0O0QAAAAAAAAAAAAAAAAAAAB code 00QAAAAAABR0000000GR000000RG  0R000011RGRQAAAAAAAAAB300000000000000R0O0QAAAAAAAAAAAAAAAAAAAB 1fdD KLFRNILKEKGIVVGIKLDQGGAPLAGT  NKETTIQGLDGLSERCAQYKKDGVDFGKWRAVLRIADQCPSSLAIQENANTLARYASICQQN site                                                          * site       *                                         * 1fdA GLVPIVEPEVIPDGDHDLEHCQYVTEKVLAAVYKALNDHHVYLEGTLLKPNMVTAGHACTKKYTPEQVAMATVTALHRTVPAAVPGICFL code R000000R0R0R00R00QAAAAAAAAAAAAAAAAAAAABR00QABG0000000000QBGRG000QAAAAAAAAAAAAB000QBGR00000 LCS  R000000R0 0R00R00QAAAAAAAAAAAAAAAAAAAABR00QABG0000000000QBGRG000QAAAAAAAAAAAAB000QBGR00000 code R000000R0O0R00R00QAAAAAAAAAAAAAAAAAAAABR00QABG0000000000QBGRG000QAAAAAAAAAAAAB000QBGR00000 1fdD GLVPIVEPEVIPDGDHDLEHCQYVTEKVLAAVYKALNDHHVYLEGTLLKPNMVTAGHACTKKYTPEQVAMATVTALHRTVPAAVPGICFL site       *                                         * site  1fdA SGGMSEEDATLNLNAINLCPLPKPWKLSFSYGRALQASALAAWGGKAENKKATQEAFMKRAVVNCQAAKGQYVHTGSSGAASTQSLF TASYTY code RRR00QAAAAAAAAAAABGRG00RG0000R00QAB1QAAAAAGRR0QABQAAAAAAAAAAAAAAAAAABRR000R000000QBR000 RGG0-- LCS  RRR00QAAAAAAAAAAAB RG00RG0000R00QA 1QAAAAA RR0QABQAAAAAAAAAAAAAAAAAABRR000 000000  R000 RG code RRR00QAAAAAAAAAAAB0RG00RG0000R00QA81QAAAAABRR0QABQAAAAAAAAAAAAAAAAAABRR000000000000R0001RGR-- 1fdD SGGMSEEDATLNLNAINLCPLPKPWKLSFSYGRALQASALAAWGGKAENKKATQEAFMKRAVVNCQAAKGQYVHTGSSGAASTQSLFTASYTY site  *RATIO :  lcs/trimmed_seq_a = 0.961 (=  345/  359), lcs/trimmed_seq_b = 0.961 (=  345/  359)

Structural alignment by ComSubstruct + manual inspection

DSSP LLLLLLLLHHHHHHHHHHHHHHHHHHLEEEEELLLHHHHHHHHHHLLLLLLHHHHHHHHHHHHLLLHHHHHLEEEEEELHHHHLLLLLLL 1fdA AHRFPALTPEQKKELSDIAQRIVANGKGILAADESVGTMGNRLQRIKVENSEENRRQFREILFTVDNSINQSIGGVILFHETLYQKDSQG      |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1fdD AHRFPALTPEQKKELSDIAQRIVANGKGILAADESVGTMGNRLQRIKVENSEENRRQFREILFTVDNSINQSIGGVILFHETLYQKDSQG DSSP LLLLLLLLHHHHHHHHHHHHHHHHHHLEEEELLLLHHHHHHHHHLLLLLLLHHHHHHHHHHHHLLLHHHHHLEEEEEELLHHHHLLLLLL DSSP LLHHHHHHHLLLEEEEELLLLEEELLLLLLLEEELLLLLHHHHHHHHHHLLLLEEEEEEEELLLLLLLLHHHHHHHHHHHHHHHHHHHHL 1fdA KLFRNILKEKGIVVGIKLDQGGAPLAGTNKETTIQGLDGLSERCAQYKKDGVDFGKWRAVLRIADQCPSSLAIQENANTLARYASICQQN      |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1fdD KLFRNILKEKGIVVGIKLDQGGAPLAGTNKETTIQGLDGLSERCAQYKKDGVDFGKWRAVLRIADQCPSSLAIQENANTLARYASICQQN DSSP LLHHHHHHHLLLEEEEELLLLEEELLLLLLLEEELLLLLHHHHHHHHHHLLLLEEEEEEEELLLLLLLLHHHHHHHHHHHHHHHHHHHHL DSSP LLEEEEEEEELLLLLLLHHHHHHHHHHHHHHHHHHHHHLLLLHHHLEELLLLLLLLLLLLLLLLHHHHHHHHHHHHHLLLLLLLLEEEEL 1fdA GLVPIVEPEVIPDGDHDLEHCQYVTEKVLAAVYKALNDHHVYLEGTLLKPNMVTAGHACTKKYTPEQVAMATVTALHRTVPAAVPGICFL      |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1fdD GLVPIVEPEVIPDGDHDLEHCQYVTEKVLAAVYKALNDHHVYLEGTLLKPNMVTAGHACTKKYTPEQVAMATVTALHRTVPAAVPGICFL DSSP LLEEEEEEEELLLLLLLHHHHHHHHHHHHHHHHHHHHHLLLLHHHLEELLLLLLLLLLLLLLLLHHHHHHHHHHHHHLLLLLLLLEEEEE DSSP LLLLLHHHHHHHHHHHHHLLLLLLLEEEEEELHHHHHHHHHHHLLLHHHHHHHHHHHHHHHHHHHHHLLLLLLLLLLllllllllllllllll 1fdA SGGMSEEDATLNLNAINLCPLPKPWKLSFSYGRALQASALAAWGGKAENKKATQEAFMKRAVVNCQAAKGQYVHTGSsgaastqslftasyty      ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| 1fdD SGGMSEEDATLNLNAINLCPLPKPWKLSFSYGRALQASALAAWGGKAENKKATQEAFMKRAVVNCQAAKGQYVHTGSsgaastqslftasyty DSSP LLLLLHHHHHHHHHHHHHLLLLLLLEEEEEELHHHHHHHHHHHLLLHHHHHHHHHHHHHHHHHHHHHLLLLLLLLLLllllllllllllllll *Z-score 60.4  AR 347  RMSD 0.8A  SI 100%

Structural alignment by DaliLite

[The DSSP code]

• H = alpha helix
• B = residue in isolated beta-bridge
• E = extended strand, participates in beta ladder
• G = 3-helix (3/10 helix)
• I = 5 helix (pi helix)
• T = hydrogen bonded turn
• S = bend
• L = no assigned structure

[The 5-tile code]

• 0 = DDDDD    (extended strand, small blue spheres)
• 1 = DDDDU
• 2 = DDDUD
• 3 = DDDUU
• 8 = DUDDD
• 9 = DUDDU
• A = DUDUD    (helix, large red spheres)
• B = DUDUU    (turn, large yellow spheres)
• G = UDDDD
• H = UDDDU
• I = UDDUD
• J = UDDUU
• O = UUDDD
• P = UUDDU
• Q = UUDUD    (turn, large yellow spheres)
• R = UUDUU    (turn, large yellow spheres)